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PLoS One (2013) 8:e54562.10.1371/journal.pone.0054562 40 HellerFFlorianPBojarskiCRichterJChristMHillenbrandBet alInterleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution

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doi:10.2105/AJPH.2007.125542

For example, adolescents are more likely to be night owls, going to bed late and waking late, compared to adults