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However, in contrast to wtp53, mutp53 fails to inhibit LRPPRC expression after DNA damage, resulting in an increase in MDR1 transcription, which leads to chemoresistance [113]
6 Its also not recommended for pregnant women, since there is some evidence that it can cross the placenta and affect fetal development I say more on this in the additional information section below
It was further confirmed that the expression of p53 in patients with liver steatosis without inflammation was significantly lower than that in NASH
Radiotherapy Radiotherapy is now considered to be one of the effective approaches to cancer treatment
The effects of several agents affecting the p53-related pathways on male infertility are shown in Table 2
Unfortunately, not everyone who smokes makes that choice