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It may also increase the risk of cancers of the larynx (voice box) and pharynx (upper throat)

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Mixed messages for women

"The message from this research is that women should quit smoking before becoming pregnant, or very early on, to reduce the chance of having a baby with a serious and lifelong physical defect." Co-author, Professor Charles Rodeck, UCL Institute for Women's Health, added: "The results of this research are of the greatest significance for the health of mothers and babies and for public health policy