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The first review was an overview of Cochrane reviews on the benefits and harms of behavioural, pharmacologic, and other (e.g., acupuncture) therapies.22 We conducted an overview of Cochrane reviews because there were existing Cochrane reviews of all interventions that would likely be considered and these reviews transparently report assessments of risk of bias and other elements important for assessing evidence certainty

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(01:02) Such was the zeitgeist power of Virginia Slims that they became the very last cigarette brand ever advertised on American TV, at 11:59 p.m on January 2, 1971, during The Tonight Show Starring Johnny Carson

And there was a period at the beginning of the 20th century where surgeons would scrape out the sinuses as a treatment for optic neuritis, he added

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Not a toy