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Within the first 15 minutes to an hour of being exposed, symptoms would create a stimulating effect such as: Nausea or vomiting Stomachache and loss of appetite Increased heart rate and blood pressure Headache Mouth watering Quick, heavy breathing Dizziness or tremors Confusion and anxiety Within 30 minutes to up to four hours later, symptoms shift and include: Diarrhea Shallow breathing Slower heartbeat and blood pressure Extreme fatigue Weakness, slow reflexes, or unable to control muscles Pale skin You will need to go to a hospital if your symptoms progress to include seizures, respiratory failure, cardiac arrest, breathing difficulties or even coma

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On the other hand, varied availability of, and access to, different substances may also have affected consumption levels

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For example, total cigarette sales per year (excluding China) have fallen by 25-30% over the last decade as more people quit and fewer people take up smoking