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Results with office injections tend to not last as long in smokers, and as a result patients may end up paying more to get their desired results

If its cold, it can become brittle

Bridges RB, Humble JW, Turbek JA, et al

19 Total for ex-cigarette smokers who stopped at ages 25-34 is observed 7, expected 4.7
Another paper from PMR, 2014 explained why

A rapid evaluation of the US federal tobacco 21 (T21) law and lessons from statewide T21 policies: findings from population-level surveys
