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With each additional drag and cigarette after it, the brains receptors for dopamine - the neurochemical that gives us a feeling of reward for doing things that are good for our survival, like eating die off

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Crittenden KS, Manfredi C, Cho YI, Dolecek TA: Smoking cessation processes in low-SES women: the impact of timevarying pregnancy status, healthcare messages, stress and health concerns

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Many would ultimately join Oppenheimer at Los Alamos