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Further, six of these 11 regions were found to be associated with diseases, such as asthma or cancer, the risk of which is known to increase with smoking

Tolerance : Tolerance requires more nicotine to achieve the same effect, as the body becomes less responsive to its stimulating properties

Gonzalez Santacruz E, Romero D, Noguez J and Wuest T (2024) Integrated quality 4.0 framework for quality improvement based on Six Sigma and machine learning techniques towards zero-defect manufacturing

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In an open letter, Shakur once posed the question: Why, I wonder, do I warrant such attention