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Remember you have two choices for interpreting this parameter

Califf, M.D., FDA Commissioner said

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People with nicotine dependence require evidence-based medical treatment and support, just as with any other chronic condition.

learning, sensory gating Genetic Studies of Nicotinic Receptor Subtypes 2 Dopamine release, self-administration (Picciotto) 4 Nicotine sensitivity (Tapper) 5, 6 Combine with 4 and 2