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The fact that this is specifically aimed at adults is important: Concerned health officials, regulators, and parents all honed in on Juul's bright and colorful ads that were splashed over social media in 2018, calling them youth-centric

95 Several pyrazine derivatives have also been found to potentiate 5-HT binding to receptors in the central nervous system, which results in enhanced dopamine release independently of nicotine

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Retrieved 4 July 2025

This may lead to symptoms including weight gain, especially around the trunk, round face, easy bruising, and high blood pressure