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Studies conducted by Zutshi et al

The reasons are relatively simple

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There is limited evidence from in vivo animal studies using intermediate biomarkers of cancer to support the hypothesis that long-term e-cigarette use could increase the risk of cancer

Therefore, smoking cessation is never too late to reduce the cardiovascular risk ( In terms of the effect of smoking on PAD after surgery, studies have shown that smoking intensity exerts an unusually large effect on the prognosis of patients with symptomatic lower extremity revascularization