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A problem with the surveys of high school seniors is that they exclude absentees at the time of the survey (about 17% of the sample) and high school dropouts (about 15% of youth at high school ages)

Homogenous leukoplakia in the early stages may be thin, flat, or slightly elevated, grey-white in color with fissures

The increase in sales relative to the number of smokers in 2020 and 2021 was the result of lockdowns and travel bans forcing smokers to buy tobacco legally in British shops

SCC in HS tends to have a high metastatic potential and poor prognosis, with studies indicating a mortality rate as high as 59% for those affected [38]

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