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Mitochondrial activity is central to glucose sensing

NICE guideline NG28 supports the use of GLP-1 receptor agonists as add-on therapy to metformin when specific criteria are met, including inadequate glucose control despite optimised treatment

Those experiencing significant GI side effects should first discuss dosage adjustment and standard management strategies with their prescribing provider

The mice were housed in ventilated cages in a humidity- and temperature-controlled room (temperature, 22 2 C

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