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Nevertheless, some beneficial effects of GLP-1RAs on albuminuria and reducing the progressive loss of kidney function have been demonstrated in LEADER, SUSTAIN 6, and REWIND (5, 6, 9, 19) and a GLP-1RA with proven CVD benefit is recommended in patients with CKD if SGLT2is are not tolerated or are contraindicated, or if eGFR is less than adequate (18)
A preliminary analysis of the data was performed to identify (1) significant outliers (box plot method) and to test (2) normality (Shapiro-Wilk test), and (3) homoscedasticity (homogeneity of variance, Levenes test) of all measured variables
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