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Understanding Nicotine Yield in Refillable Vapes Refillable vape devices introduce a significant amount of variability in nicotine intake compared to traditional cigarettes and disposable vapes

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It is important to note that dual useusing both cigarettes and vaping productscan increase exposure to toxins and worsen respiratory health outcomes, making it an ineffective harm reduction strategy

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In addition, some components of cigarette smoke activate PKC, resulting in increased expression of monocyte adhesion ligand CD11b, further enhancing monocyte adhesion to endothelium [48]