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A 2006 study by Imperial Tobacco Tobacco Product Illicit Trade Phenomena found that approximately 1 in 4 cigarettes smoked in Ontario and Quebec were illegal

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Founded in 1910 as the Imperial Tobacco Company, ITC initially focused on tobacco and cigarette manufacturing

The 2017 international classification of EDS recognizes 13 subtypes that are caused by pathogenic variants in 19 different genes, mainly encoding fibrillar collagens, collagen-modifying proteins, or processing enzymes [1]