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It is now considered the worlds single biggest cause of preventable death

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Gilbert patented a device describe as a smokeless non-tobacco cigarette where he heated moist, flavored air instead of burning actual tobacco

"Citizens and the cigarette: The civic dimensions of America's earliest, youth-targeted, mass-mediated anti-cigarette campaign." Journal of consumer culture 13.1 (2013): 324

[17] More serious effects were bradycardia, hypotension, nausea, respiratory paralysis, atrial fibrillation and dyspnea