comparing glp-1 agonists Frontiers Glucagon-Like Peptide 1 Receptor Agonists

You might hear them called GLP-1 analogs or incretin mimetics. While the first version was approved in 2005, modern options like Ozempic, Wegovy, and Zepbound have revolutionized the field by offering once-weekly dose to get superior results

Liraglutide is the oldest of the three and has the most evidence for antipsychotic-induced weight gain, with positive results from two small RCTs in schizophrenic disorders at a dose of 1.83.0 mg/day (Lee K et al, Gen Hosp Psych 2022;78:5867)

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Study identifies benefits, risks linked to weight-loss drugs. WashU Medicine

Therefore, future studies should focus on exploring unknown pathways and their corresponding effects, thereby correlating cellular-level changes with genetic modifications to clarify the relationship between outcomes and functions, which could further facilitate clinical applications