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Jamess disdain for the noxious plant led him to levy a heavy excise tax on tobacco brought from North America, but 20 years later the ever-increasing demand for tobacco led him to do an about-face and create a royal monopoly for the crop

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Based on previous reports on EEG biomarkers associated with smoking, we hypothesized that resting state EEG (rsEEG) powers measured from chronic smokers, past-smokers, and never-smokers would reveal neural changes associated with chronic smoking apart from the changes unobservable in past-smokers, as if they are recovered with successful long-term abstinence