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and has a very attractive remuneration package. A week later, I sent the following reply: Thank you for your thoughtful letter

The meta-analytic tool overcomes many of the limitations of traditional meta-analyses by incorporating between-study heterogeneity into the uncertainty of risk estimates, accounting for small numbers of studies, relaxing the assumption of log(linearity) applied to the risk functions, handling differences in exposure ranges between comparison groups, and systematically testing and adjusting for bias due to study designs and characteristics

Because these businesses frequently use marketing methods to target these populations, FDA must consider community demographic makeup and marketing efforts when formulating new regulations on e-cigarettes, she contends

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