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Stable CHOFlpIn expression cell lines were selected using 600 g/ml hygromyocin B, and maintained in DMEM supplemented with 5% (V/V) FBS (Invitrogen) at 37C in 5% CO 2

Brain-derived neurotrophic factor (BDNF) is important for neurogenesis, and various depressive symptoms arise from decreased BDNF levels (Sahay and Hen, 2007)

Regression of MASH showed dose dependency, with the 15 mg dose exhibiting the best response at 62% (vs

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