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In addition, p53 also plays an important role in anti-tumour immunity through the regulation of innate and adaptive immune profiles [174] and/or the expression of immune-inhibitory checkpoint regulators by the cancer cells [175]

Of note, cells lacking FAS (e.g

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When the chemicals in cigarette smoke cause atherosclerosis and thickened blood in the arteries, it becomes more difficult for blood cells to move through arteries and other blood vessels to get to vital organs like the heart and brain

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