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The company said the changes are intended to create a more agile, technology-enabled organization capable of responding more quickly to changing market conditions and accelerating its transition toward reduced-risk products

The researchers also examined lung health risk among light smokers, which they defined as having less than a 10 pack-years smoking history

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The scale of the cutbacks, Mould cautioned, was "a sign of the times" and a worrying signal for the wider jobs market.

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