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Blood pressure significantly and progressively increased throughout the 60-week exposure period in all electronic cigarette exposure groups and the traditional cigarette exposure groups Vascular function was impaired in the electronic cigarette and traditional cigarette groups, which was observed as early as 16-weeks into the exposure period Left-ventricular mass progressively increased in electronic cigarette and traditional cigarette groups throughout the 60-week exposure period Both the electronic cigarette and traditional cigarette groups had increased heart weight at 60-weeks Thickness of the aortic wall was increased in all of the cigarette exposure groups, with greater changes in the traditional cigarette group vs