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FDA considered this information in identifying 15 revised statements [5] for further quantitative (see section VI.C) and qualitative (see section VI.D) testing

If the p-value was less than 0.05, the groups were significantly different

Indian Journal of Psychiatry

66 To determine if there are grounds to withdraw or temporarily suspend a PMTA order, FDA can require by regulation, or on an application-by-application basis, that applicants establish and maintain records, and provide postmarket surveillance reports to FDA following PMTA marketing authorization

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Building on previous discoveries, recent research has revealed that exogenous factorsparticularly cigarette smoke exposurecan fundamentally remodel this dynamically balanced architecture via nicotine-mediated epigenetic pathways (Table 3)