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While fluconazole is generally safe and effective when prescribed, combining it with alcohol can interfere with its efficacy and lead to unwanted side effects

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More of their friends and family smoke, and many live and work in places where indoor smoking is allowed

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Thus, it is possible that estradiol and progesterone act together, through ALLO, to increase GABAergic tone and, in turn, attenuate the rewarding properties of nicotine