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30 observed that, among smokers who were acutely abstinent (12 h) and either completely deprived of nicotine or were using nicotine gum only, a smaller change in diastolic blood pressure in response to a videotaped speech was observed in OC users as compared to the nonusers

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To conclude, the studies suggesting a positive effect of nicotine on muscle regeneration and development were all conducted on murine models, whereas the ones suggesting the negative effect were done on humans