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[2] Despite claims that senators appointed by legislatures were more apt to be corrupted, there is scant evidence that this was actually the case

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Based on these reviews, we identified cohort and case-control studies that either reported a measure of association or contained sufficient information to calculate a measure of association between the incidence or mortality of the identified outcomes for tobacco chewers relative to individuals who do not chew tobacco

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Research shows that this results in a substantial reduction in exposure to Harmful and Potentially Harmful Constituents (HPHCs) relative to cigarette use