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doi: 10.1002/sim.3255 [DOI] [PMC free article] [PubMed] [Google Scholar] 48.svold BO, Bjrngaard JH, Carslake D, et al

Chronic carbon monoxide exposure can increase carboxyhemoglobin concentration up to 10% in heavy smokers, producing a functional anemia and related hypoxemia (5)

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First-time or infrequent users typically experience stronger, longer-lasting effects compared to regular users