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As Thurnham defined, a well-balanced diet should contain ‘the adequate micronutrients to sustain body functions, but also a wide range of non-nutrients to optimize phase I (oxidation) and phase II (conjugation) metabolic processes’ [28]

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Another example is cyclopropane, a carboxylic acid derivative that, when combined with colistin, potentiates the antibiotic against both gram-positive and gram-negative bacteria 147,148,149