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Under these oxidizing conditions, S-glutathionylation may serve as a reservoir for GSH inside the cell and may also protect from irreversible oxidation to sulfinic and sulfonic acid, which leads to proteasomal degradation of the protein (209)

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Why a Weight-Based Approach Is More Appropriate in Glutathione Dosing Glutathione (GSH) is a tripeptide synthesized in the liver and is central to the body’s natural antioxidant defense system