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Potentially Detrimental Consequences of Slowed Gastric Emptying and Other Effects of GLP-1 RAs on Gastrointestinal Motility RAs and the Risk of Small Bowel Obstruction or Ileus IV infusions of native GLP-1 that achieve either physiological or supraphysiological plasma concentrations are associated with inhibition of the migrating motor complex (83) and a decrease in the number and amplitude of duodenal pressure waves during both fasting and intraduodenal lipid infusion (14)