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Diagnosis Conventional diagnostic criteria for diabetes include: Fasting plasma glucose 126 mg/dL or greater, Non-fasting plasma glucose level 200 mg/dL or greater with diabetes symptoms, Plasma glucose level 200 mg/dL or greater 2 hours after a 75-g oral glucose tolerance test, or HbA1C 6.5% or greater Note: Life Extension suggests targeting a fasting glucose level of 80 – 86 mg/dL and a HbA1C level of 5 – 5.4%