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Studies using this isolated actin-binding fragment found it retained close to the full peptide's angiogenic activity in endothelial migration and vessel-sprouting assays, pointing to actin regulation — not growth-factor signaling — as the operative mechanism

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→ In Canada and most of the European Union, it’s not approved for medical or cosmetic use and is considered an unregulated compound (Health Canada advisory listing AOD9604 as unauthorized)