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In summary, GLP-1RAs provide substantial weight loss and cardiometabolic benefits but may compromise skeletal muscle integrity, whereas exercise supports muscle maintenance and functional health, though its effect on weight reduction is typically modest compared with pharmacotherapy

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The limitation: During the MOMENTUM trial, participants also exercised more, so isolating the drugs impact is difficult

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2531), and anti-AMPK antibody (Cell Signaling, Catalog No

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doi: 10.3109/07420528.2014.897711 29 MochelJPDanhofM

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[DOI] [PubMed] [Google Scholar] 171

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Note: Compounded Semaglutide and Compounded Tirzepatide are prepared by FDA-registered, inspected compounding pharmacies to meet specific patient needs

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