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Description
Many trials were designed to explore cardiovascular safety or benefit using SGLT2i molecules, including empagliflozin, dapagliflozin, canagliflozin, and ertugliflozin, which greatly differ in their characteristics, including the number of participants, study duration, the inclusion of patients with HF or renal disease, HF characterized by reduced ejection fraction (HFrEF) or preserved ejection fraction (HFpEF), and associated comorbidities or risk factors, clearly implying differences in the risk and rate of cardiovascular or renal events recorded during the investigations [2]

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Before beginning a treatment plan, prequalify the prescription with the patients insurer

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Januvia is taken orally once daily and is generally well tolerated

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