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Someone may want to speak to their prescriber if they notice reduced interest in several areas, including: Friendships and social plans Exercise or movement they previously enjoyed Hobbies and creative interests Romantic relationships or intimacy Work, goals or everyday routines Music, entertainment or other pleasurable experiences The timing of these changes can also be useful

Materials and Methods The study was designed in agreement with the 2020 Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement guidelines and it was registered in the PROSPERO database (Registration number CRD42022350115) [15]