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Some patients cycle on and off medication based on affordability rather than medical indication
This change in normal digestive rhythm, combined with dietary modifications and activation of GLP-1 receptors in the intestinal lining, can lead to changes in bowel habits including diarrhea in some patients

[DOI] [PubMed] [Google Scholar] 173.Zahid, M

These are lower molecular-weight compounds (orforglipron ~600 Da) and avoid peptide-specific issues, so their supply chains resemble those of standard APIs
