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Dose Escalation: The temporal relationship between medication initiation or dose escalation and symptom onset strengthens the potential causal association identified through pharmacovigilance monitoring

Jossy Onwude, MD Reviewed by Kenya Bass, PA-C Published Jul 8, 2025 13 min read Melatonin has become one of the most popular supplements for sleep, and for good reason

Increase the amount of fiber in your food and also drink more water

Nausea becomes more frequent and more severe

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Any data beyond what is reported in the manuscript, including but not limited to the raw EHR data, cannot be shared or released due to the parameters of the expert determination to maintain the data de-identification