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The progressive form, MASH, exhibits hepatocyte damage, inflammatory cell infiltration, and variable degrees of tissue fibrosis, with advanced fibrosis representing the predominant prognostic determinant for hepatic morbidity and mortality, as well as an additional risk factor for extrahepatic complications

Using some naive assumptions here (that the average weight loss required for the average obese persons BMI to be below 30 and thus not categorized as obese, assuming x% of obese people take the drug and all experience the average reduction in body weight), we can see a picture emerge that shows the potential to disrupt a trend thats been forming for the past 50 years

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Post-meal pharmacodynamic profile of AVE0010, a once-daily GLP-1 receptor agonist, in patients with type 2 diabetes inadequately controlled on metformin (Abstract) Diabetologia

Mounjaros active ingredient works as a dual agonist for the GLP-1 (glucagon-like peptide-1) receptor and the GIP (glucose-dependent insulinotropic polypeptide) receptor

In simpler terms, each heartbeat pushes more blood with more force