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Common side effects associated with GLP-1 receptor agonists in published clinical literature include nausea, vomiting, diarrhea, constipation, and abdominal discomfort
Interestingly, DPP-4 activity was associated with risks of major adverse cardiac or cerebrovascular events (cardiovascular mortality, myocardial infarction, heart failure-HF readmission, stroke, non-cardiovascular mortality, and repeated revascularization) in T2D patients with ST-segment elevation myocardial infarction (STEMI) [71]
By targeting the brains reward system, these drugs could help curb cravings for addictive substances like alcohol, nicotine, and opioids
You can read the abstract of this article at 104-OR: Novel GIP/GLP-1/Glucagon Receptor Agonist LY3437943: A First-in-Human Dose Study in Healthy Subjects | Diabetes | American Diabetes Association (diabetesjournals.org)
[DOI] [PubMed] [Google Scholar] 800.Wettergren A., Wojdemann M., Holst J.J
Novo Nordisk, the maker of Ozempic, is named as a defendant in the multidistrict litigation for people claiming blindness from GLP-1 drugs (MDL No
