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The pathophysiology of septic lung injury is complex, involving disruption of the alveolarcapillary barrier, interstitial edema, vascular congestion, and infiltration of inflammatory cells, ultimately leading to profound impairment of gas exchange and tissue integrity (Swenson and Swenson 2021

104 In addition to the pharmacological classification and mechanistic insights into natural products used in GI health, numerous ethnobotanical and ethnopharmacological surveys across the globe provide compelling evidence of traditional plant use in treating a wide range of GI disorders

In contrast, the gut microbial metabolite short-chain fatty acids (SCFAs) can regulate the maturation, development, and immune responses of innate immune cells, such as microglia, and influence organ-specific autoimmunity (Sadler et al., 2020)

Second, aNDBs consist of positively charged molecules (chondroitin sulfate, o-pullulan, alginate, -polylysine, chitosan, magainin-2, etc.), containing cationic groups such as quaternary ammonium, quaternary phosphonium, guanidinium, or tertiary sulfonium (Santos et al., 2016), which have a positive charge

Martnez Damonte, S

The pretreatment of cultured rat hepatocytes with UDCA significantly prevents the decrease in viability due to H 2 O 2 or cadmium administration [77]