2023 international evidence-based guideline pcos glp-1 receptor agonist Polycystic ovary syndrome: An update on diagnosis and management GLP-1s Lead to Greater Weight
Description
Whether the use of GLP-1RAs could interfere with this signal, which is being explored for early detection of PDAC, is uncertain 47,48
The black box warning was given to Ozempic because of the increased risk of thyroid C-cell tumors, including medullary thyroid carcinoma
But GLP-1 also has an indirect effect on the liver (by lowering hepatic gluconeogenesis) and the brain (by increasing neuroprotection) [56]
M.et al (2022)
doi: 10.1210/clinem/dgab722 63 WilsonJMLinYLuoMJConsidineGCoxALBowsmanLMet al
This discouraged the pharmaceutical industry from developing such drugs and undermined the FDA's willingness to approve them
