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Exendin-4 exposure also led to a significant reduction in the level of reactive oxygen species (ROS) in Control shRNA islets exposed to thapsigargin, but this effect was no longer present in SPHKAP shRNA-transduced islets, which presented with basally higher ROS levels than the corresponding control islets (Fig

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doi: 10.1210/en.2014-1717

those with mild AD dementia were required to have a CDR global score of 1.0

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