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In conclusion, the paper provides evidence that the reduction of GLP-1+ cells is a general feature of ileal and colonic inflammation in mice and humans and is likely due to altered epithelial differentiation driven by changes in cellular metabolism, particularly mitochondrial dysfunction.
Explore the GLP-1 drug pipeline in 2026: new approvals, retatrutide's 28% weight loss, CagriSema, oral agents, and expanding indications.
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