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Figure 29: Photograph of Professor Catherine rskov, credit: rskov

Benefits Timeline Week 1-2: Food noise reduction, quieting of cravings begins Month 1: 2-4 pound loss typical, nausea under 10% for microdosers Month 3: 5-8% total body weight loss sustained Microdosing can support natural satiety and mindful eating, making it easier to build sustainable healthy habits rather than relying solely on the medication

However, medicines such as semaglutide and liraglutide have been extensively investigated, and a majority of the adverse effects of GLP-1 medications are similar and mainly gastrointestinal 1

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Holst JJ (2021) Treatment of type 2 diabetes and obesity on the basis of the incretin system: the 2021 Banting Medal for Scientific Achievement award lecture

In clinical trials, these medications led to a 15 to 20% reduction in body weight when paired with a reduced-calorie diet and regular exercise
