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Individuals with a history of pancreatitis, medullary thyroid cancer, or severe gastrointestinal issues, as well as anyone allergic to GLP-1 receptor agonists, should discuss potential risks and benefits with their provider before starting treatment
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The temporal distribution of AE onset demonstrated a median time of 59 days (interquartile range: 16212 days), indicating substantial variability in the latency period of adverse events
The reported case timeframe also suggests detection bias rather than causation, necessitating further long-term studies to evaluate this risk [64]
2.5 Alkaline phosphatase (ALP) staining To assess ALP expression 7 days after osteogenic induction, an ALP staining kit (Beyotime, China) was used
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