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The Plateau Problem - Why GLP-1 Therapies Stop Working (and What To Do About It) Share The Plateau Problem Why GLP-1 Therapies Stop Working (and What To Do About It) GLP-1 therapies like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have delivered remarkable results for many patientsbut for a growing number, theres a common frustration: It was working and then it wasnt. Weight loss slows

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[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Overgaard R.V., Lindberg S.O., Thielke D

Expect body-composition shifts over months, not dramatic weight loss

You may have seen this tip floating around social media: injecting in the thigh (or upper arm) instead of the stomach can reduce nausea