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Yet few people have a full understanding how GLP-1 affects the body.

The authors discuss the preclinical literature and emerging clinical evidence that support the rationale for investigating the use of glucagon-like peptide-1 receptor agonists to prevent and treat several neurodegenerative diseases of aging, with a focus on Alzheimers disease.

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Tirzepatide (Mounjaro) is a dual-action medication for type 2 diabetes and obesity, offering blood sugar control and weight loss, with potential side effects.

Although people appear to regain weight rapidly after taking GLP-1 weight-loss drugs this may plateau after time.

Now the challenge was to find a small molecule that also fits that pocket