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Background Despite the effectiveness of glucagon-like peptide-1 agonist (GLP-1A) in the treatment of diabetes, its large molecular weight and high hydrophilicity result in poor cellular permeability, thus limiting its oral bioavailability

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60 units per week from a 5 mg/mL semaglutide solution using a standard 100-unit insulin syringe equals 3 mg per week

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